I have 64+ R730xd nodes at work, we use the HBA330 in all of them.
They work great! They were purchased as "ready-nodes" but I dont think there is much difference. Support seems to be from the same team as regular nodes. One thing our rep did say if they are set to Maximum Performance in the BIOS from the factory. Not sure what else is different from regular nodes. Like I said I dont think all that much. You still use all the same drives/firmware/Dell ESXi loads from support.dell.com